INNER EAR THERAPEUTICS: UPDATES AND CHALLENGES FOR APPLICATIONS

Program Overview

April 28-30th, 2023

Federico MINGOZZI, Chief Science &TechnologyOfficer, SparkTherapeutics, Philadelphia, USA
Title: Progress and Challenges in the Development of In Vivo Gene Therapies with AAV Vectors

Gabriel CORFAS, Kresge Hearing Research Institute, University of Michigan, Ann Arbor, USA
Title: Hidden Hearing Loss: Pathogenic Mechanisms and Potential Therapeutic Approaches

Charles LIBERMAN, Harvard Medical School, Mass Eye and Ear Infirmary, Boston, USA
Title: Noise- and Age-related Hearing Loss in Humans and Animals: New Insights and Novel Therapies

Zheng-Yi CHEN, Harvard Medical School, Mass Eye and Ear Infirmary, Boston, USA
Title: Treatment of Autosomal Dominant Hearing Loss By In Vivo Delivery of Genome Editing Agents

Shin-Ichi USAMI, Shinshu University School of Medicine, Nagano, Japan
Title: Could the Genetic Origin of Sensorineural Hearing Loss Affect the Outcomes of Cochlear Implantation?

Thomas LENARZ, Department of Otolaryngology, Hannover Medical School, Hannover, Germany.
Title: Extracellular Vesicles in Inner Ear Therapies: Pathophysiological, Manufacturing, and Clinical Considerations

Yann NGUYEN, Institut de l’Audition AP-HP Sorbonne University, Paris, France
Title: Robot-Based Cochlear Implant Insertion

Marta ROCCIO, Inner Ear Stem Cell Lab, Department Otorhinolaryngology Head and Neck Surgery, University Hospital Zurich and University of Zurich, Switzerland
Title: Human Inner Ear Organoids: A New Tool to Probe Hearing Restoration Therapeutics

Vincent VAN ROMPAEY, Faculty of Medicine and Health Sciences, Antwerp, Belgium
Title: Disease-modifying therapy for autosomal dominant hereditary hearing loss in DFNA9

Michael R. BOWL, University College London Ear Institute, London, United Kingdom
Title: Background Check: Using the Mouse to Elaborate on the Genetics of Mammalian Hearing

Jeffrey HOLT, Harvard Medical School, Boston Children's Hospital, Boston, USA
Title: Function, dysfunction and restoration of sensory transduction channels in auditory hair cells

Erwin VAN WYK, Radboud University Medical Center, Nijmegen, Netherlands
Title: RNA Therapies for Otogenetic Disorders: Current Status

Wade CHIEN, Johns Hopkins School of Medecine, Baltimore, USA
Title: Applications of Dual-AAV Gene Delivery to Mouse Models of Hereditary Hearing Loss

Isabelle MOSNIER, AP-HP, Sorbonne University, Paris, France
Title: Candidacy for Cochlear Implantation in Prelingual Profoundly Deaf Adult Patients

Hinrich STAECKER, Department of Otolaryngology, Hannover Medical School, Hannover, Germany
Titile: Gene Editing Rescues Hearing in the Shaker-1 Mouse Model of Usher Syndrome Type-1B

Christine PETIT, Institut de l’Audition/Institut Pasteur, Paris, France
Title: Sensorineural Deafness: From Genetic Architecture to Gene Therapy

Charles C. DELLA SANTINA, Johns Hopkins School of Medicine, Baltimore, USA
Title: Vestibular Implantation and Long-Term, Continuously Motion-Modulated Stimulation to Treat Patients Disabled by Bilateral Vestibular Hypofunction

Nils GUINAND, Clinical Neurosciences, University Hospital, Geneva, Switzerland
Title: The Cochleo-Vestibular Implant: Update and Remaining Challenges

Athanasia WARNECKE, Head and Neck Surgery Hannover Medical School, Germany
Title: Perilymph Diagnostics: A New Possibility for the Development of Precision Treatment?

Bernard FRAYSSE,
Title: Prognostics Factors of hearing Aids Outcomes: A Big Data Analysis

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